Filorexant
Filorexant (MK-6096) is a potent, selective, and orally bioavailable dual antagonist of orexin receptors OX1 and OX2, with sub-nanomolar binding affinity. It is a valuable research tool for investigating sleep disorders and has been utilized in both in vitro binding assays and in vivo preclinical models of insomnia.
Product Specifications
CAS Number
1088991-73-4
Product Name Alternative
HCRT Receptor, Filorexant, Hypocretin Receptor, MK 6096, MK6096, MK-6096, Orexin receptor, Orexin Receptor (OX Receptor), OXReceptor, OX1, OX Receptor, OX2, Inhibitor, inhibit
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.88% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.51 mM) ; DMSO:100 mg/mL (237.82 mM)
Smiles
C[C@@H]1CC[C@@H] (COc2ccc (F) cn2) CN1C (=O) c1cc (C) ccc1-c1ncccn1
Molecular Formula
C24H25FN4O2
Molecular Weight
420.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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