Islatravir
Islatravir (MK-8591) is a potent nucleoside reverse transcriptase inhibitor effective against HIV-1, including resistant strains like M184V and MDR variants. It is a key research compound for investigating antiviral mechanisms and therapeutic strategies in both in vitro and in vivo models.
Product Specifications
CAS Number
865363-93-5
Product Name Alternative
Reverse Transcriptase, ReverseTranscriptase, inhibit, Islatravir, Inhibitor, MK8591, MK-8591, MK 8591, Human immunodeficiency virus, HIV, HIV Protease, HIVProtease, HIV-1 WT, HIV-1, HIV-1 M184V, HIV-1 MDR
Field of Research
Infectious Disease & Virology, Protein Biochemistry
Purity
97.03% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (13.64 mM) ; DMSO:100 mg/mL (341.01 mM) ; H2O:3 mg/mL (10.23 mM)
Smiles
Nc1nc (F) nc2n (cnc12) [C@H]1C[C@H] (O) [C@@] (CO) (O1) C#C
Molecular Formula
C12H12FN5O3
Molecular Weight
293.25
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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