ML792
ML-792 is a potent and selective small molecule inhibitor of the SUMO-activating enzyme (SAE), demonstrating IC50 values of 3 nM and 11 nM against SAE/SUMO1 and SAE/SUMO2, respectively. It is a valuable research tool for investigating SUMOylation in cancer biology and DNA damage response pathways in both cellular and in vivo models.
Product Specifications
CAS Number
1644342-14-2
Product Name Alternative
SAE/SUMO1, SAE/SUMO2, Ubiquitin activating enzyme, Ubiquitin conjugating enzyme, Ubiquitin ligase, inhibit, ML792, ML-792, ML 792, Inhibitor, E3Enzyme, E3 ligating enzyme, E3 Enzyme, E2Enzyme, E2 Enzyme, E1 Enzyme, E1/E2/E3 Enzyme, E1 activating enzyme, E1Enzyme, E2 conjugating enzyme
Field of Research
Protein Biochemistry
Purity
>98%
Form
Powder
Solubility
Soluble in DMSO (at least 65 mg/ml)
Smiles
NS (=O) (=O) OC[C@H]1C[C@H] (C[C@@H]1O) Nc1ncncc1C (=O) c1ccn (Cc2cccc (Br) c2) n1
Molecular Formula
C21H23BrN6O5S
Molecular Weight
551.4
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
[ (1R,2S,4R) -4-[[5-[1-[ (3-Bromophenyl) methyl]pyrazole-3-carbonyl]pyrimidin-4-yl]amino]-2-hydroxycyclopentyl]methyl sulfamate
Available Sizes
Frequently Asked Questions
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