ML402
ML402 (ZINC3671497) is a small molecule activator of the TREK-1 and TREK-2 potassium channels, exhibiting EC50 values of 13.7 μM and 5.9 μM, respectively. This compound is a valuable research tool for investigating the roles of these channels in pain perception, depression, and neuroprotection in both cellular and animal models.
Product Specifications
CAS Number
298684-44-3
Product Name Alternative
ML 402, ML402, ML-402, N-[2- (4-chloro-2-methylphenoxy) ethyl]thiophene-2-carboxamide, TREK-2, TREK-1, ZINC3671497, ZINC-3671497, ZINC 3671497, Potassium Channel, PotassiumChannel
Field of Research
Pharmacology & Drug Discovery
Purity
98.93% (May vary between batches)
Solubility
DMSO:95 mg/mL (321.18 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (11.16 mM)
Smiles
Cc1cc (Cl) ccc1OCCNC (=O) c1cccs1
Molecular Formula
C14H14ClNO2S
Molecular Weight
295.78
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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