Isotretinoin
Isotretinoin (13-cis-Retinoic acid) is a natural retinoic acid that activates nuclear RARs to modulate gene expression, promoting cellular differentiation and apoptosis. It is widely used in oncology, dermatology, and immunology research, demonstrating antineoplastic, anti-inflammatory, and keratinization-inhibiting effects in both in vitro and in vivo studies.
Product Specifications
CAS Number
4759-48-2
Product Name Alternative
13-cis-Retinoic acid, anticancer, Autophagy, Inhibitor, EndogenousMetabolite, Endogenous Metabolite, orally active, Isotretinoin, inhibit, severe acne, RAR/RXR, RAR, Retinoic acid receptors, Retinoid Receptor, Retinoid X receptors, RetinoidReceptor, vitamin A
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery
Purity
97.01% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.66 mM) ; Ethanol:1 mg/mL (3.33 mM) ; DMSO:250 mg/mL (832.11 mM)
Smiles
C (=C/C (=C/C=C/C (=C\C (O) =O) /C) /C) \C=1C (C) (C) CCCC1C
Molecular Formula
C20H28O2
Molecular Weight
300.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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