MLi-2
MLi-2 is a brain-penetrant, highly selective LRRK2 kinase inhibitor with sub-nanomolar potency in biochemical, cellular binding, and phospho-Ser935 dephosphorylation assays. This tool compound is widely used in Parkinson's disease research for investigating LRRK2 biology and pathogenesis in both in vitro and in vivo models.
Product Specifications
CAS Number
1627091-47-7
Product Name Alternative
Disease, Leucine-rich repeat kinase 2, Parkinson's, LRRK2, orally, MLi 2, MLi2, MLi-2, Inhibitor, inhibit
Field of Research
Cell Biology
Purity
98.96% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.27 mM) ; DMSO:60 mg/mL (158.12 mM)
Smiles
C[C@H]1CN (C[C@@H] (C) O1) c1cc (ncn1) -c1n[nH]c2ccc (OC3 (C) CC3) cc12
Molecular Formula
C21H25N5O2
Molecular Weight
379.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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