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MLN-4760

MLN-4760 is a potent and selective inhibitor of human angiotensin-converting enzyme 2 (ACE2; IC50=0.44 nM) . It exhibits >5000-fold selectivity over related enzymes like ACE and carboxypeptidase A. This compound is a valuable research tool for studying ACE2 function in vitro and in SARS-CoV-2 viral entry mechanisms.

Product Specifications

CAS Number

305335-31-3

Product Name Alternative

Human ACE2, Inhibitor, MLN4760, MLN-4760, MLN 4760, inhibit, ACE, Angiotensin-converting Enzyme (ACE), Bovine carboxypeptidase A

Field of Research

Metabolism Research

Purity

99.05% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.67 mM)

Smiles

CC (C) C[C@H] (N[C@@H] (Cc1cncn1Cc1cc (Cl) cc (Cl) c1) C (O) =O) C (O) =O

Molecular Formula

C19H23Cl2N3O4

Molecular Weight

428.31

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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