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MPI_5a

MPI_5a is a potent and selective HDAC6 inhibitor (IC50=36 nM) with minimal activity against other HDAC isoforms. It effectively reduces cellular acyl-tubulin levels (IC50=210 nM), making it a valuable chemical probe for studying HDAC6 biology in cancer, neurodegeneration, and other research areas both in vitro and in vivo.

Product Specifications

CAS Number

1259296-46-2

Product Name Alternative

Acyl, accumulation, isoform, MPI_5a, inhibit, Inhibitor, HDAC, HDAC6, Histone deacetylases, selective, tubulin

Field of Research

Epigenetics & Chromatin, Molecular Biology

Purity

99.16% (May vary between batches)

Solubility

DMSO:247.5 mg/mL (826.87 mM)

Smiles

C (=O) (N1CC=2C (=CC (C (NO) =O) =CC2) CC1) C=3N (C) C=CC3

Molecular Formula

C16H17N3O3

Molecular Weight

299.32

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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