MPI_5a
MPI_5a is a potent and selective HDAC6 inhibitor (IC50=36 nM) with minimal activity against other HDAC isoforms. It effectively reduces cellular acyl-tubulin levels (IC50=210 nM), making it a valuable chemical probe for studying HDAC6 biology in cancer, neurodegeneration, and other research areas both in vitro and in vivo.
Product Specifications
CAS Number
1259296-46-2
Product Name Alternative
Acyl, accumulation, isoform, MPI_5a, inhibit, Inhibitor, HDAC, HDAC6, Histone deacetylases, selective, tubulin
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
99.16% (May vary between batches)
Solubility
DMSO:247.5 mg/mL (826.87 mM)
Smiles
C (=O) (N1CC=2C (=CC (C (NO) =O) =CC2) CC1) C=3N (C) C=CC3
Molecular Formula
C16H17N3O3
Molecular Weight
299.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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