MT-802
MT-802 is a potent PROTAC-based BTK degrader with a DC50 of 1 nM. It is a research tool for investigating Bruton's tyrosine kinase (BTK) biology and has shown potential in preclinical studies targeting C481S mutant chronic lymphocytic leukemia (CLL) in cellular models.
Product Specifications
CAS Number
2231744-29-7
Product Name Alternative
Inhibit, MT802, MT-802, MT 802, Inhibitor, Bruton tyrosine kinase, Btk, BTK, PROTAC, PROTACs
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
95.93% (May vary between batches)
Solubility
DMSO:135 mg/mL (171.36 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (5.08 mM)
Smiles
NC1=C2C (=NN (C2=NC=N1) C3CCN (CCOCCOCC (NC=4C=C5C (=CC4) C (=O) N (C5=O) C6C (=O) NC (=O) CC6) =O) CC3) C7=CC=C (OC8=CC=CC=C8) C=C7
Molecular Formula
C41H41N9O8
Molecular Weight
787.82
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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