Mutant IDH1 inhibitor
This small molecule inhibitor potently targets the mutant IDH1 R132H enzyme with an IC50 under 72 nM. It is a valuable research tool for investigating oncogenic mechanisms in models of glioma and AML, supporting both in vitro and in vivo studies.
Product Specifications
CAS Number
1429180-08-4
Product Name Alternative
IsocitrateDehydrogenase, IsocitrateDehydrogenase (IDH), Isocitrate Dehydrogenase (IDH), Mutant IDH1 inhibitor, Mutant IDH-1 inhibitor, mutant IDH1 R132H, Isocitrate Dehydrogenase, inhibit, IDH, Inhibitor
Field of Research
Metabolism Research, Metabolism Research; Pharmacology & Drug Discovery
Purity
97.72% (May vary between batches)
Solubility
DMSO:30 mg/mL (64.3 mM)
Smiles
CC (C) [C@H]1COC (=O) N1c1ccnc (N[C@@H] (C) c2ccc (CN3CCN (CC3) C (C) =O) cc2) n1
Molecular Formula
C25H34N6O3
Molecular Weight
466.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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