Lopinavir
Lopinavir (ABT-378) is a peptidomimetic inhibitor of HIV-1 protease that maintains efficacy against the Val82 mutant variant and exhibits reduced serum protein binding compared to ritonavir. It is widely used in antiviral research for in vitro enzyme assays and in vivo studies of HIV infection and resistance mechanisms.
Product Specifications
CAS Number
192725-17-0
Product Name Alternative
Coadministration, ABT378, ABT-378, ABT 378, infection, inhibit, mutant, Lopinavir, Inhibitor, Human immunodeficiency virus, HIV protease, HIVProtease, HIV Protease, HIV, SARS-CoV, SARS coronavirus, SARSCoV, replication, wild-type
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (6.36 mM) ; DMSO:247.5 mg/mL (393.61 mM) ; Ethanol:116 mg/mL (184.48 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
[C@@H] (C (N[C@@H] (CC1=CC=CC=C1) C[C@@H] ([C@H] (CC2=CC=CC=C2) NC (COC3=C (C) C=CC=C3C) =O) O) =O) ([C@@H] (C) C) N4C (=O) NCCC4
Molecular Formula
C37H48N4O5
Molecular Weight
628.8
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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