NI-42
NI-42 is a structurally orthogonal and biased chemical probe that potently and selectively inhibits the bromodomains of BRPF1, BRPF2, and BRPF3. This tool compound is valuable for investigating the roles of BRPF proteins in epigenetic regulation, cancer biology, and both in vitro and in vivo disease models.
Product Specifications
CAS Number
1884640-99-6
Product Name Alternative
BRD7, BRD9, BRD4 BD1, BD1-BRD4, BRPF2, BRPF1, BRPF3, Epigenetic Reader Domain, EpigeneticReaderDomain, inhibit, Inhibitor, NI 42, NI42, NI-42
Field of Research
Epigenetics & Chromatin
Purity
99.17% (May vary between batches)
Solubility
DMSO:95 mg/mL (268.82 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (9.34 mM)
Smiles
Cc1cc2cc (NS (=O) (=O) c3ccc (cc3) C#N) ccc2n (C) c1=O
Molecular Formula
C18H15N3O3S
Molecular Weight
353.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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