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NI-42

NI-42 is a structurally orthogonal and biased chemical probe that potently and selectively inhibits the bromodomains of BRPF1, BRPF2, and BRPF3. This tool compound is valuable for investigating the roles of BRPF proteins in epigenetic regulation, cancer biology, and both in vitro and in vivo disease models.

Product Specifications

CAS Number

1884640-99-6

Product Name Alternative

BRD7, BRD9, BRD4 BD1, BD1-BRD4, BRPF2, BRPF1, BRPF3, Epigenetic Reader Domain, EpigeneticReaderDomain, inhibit, Inhibitor, NI 42, NI42, NI-42

Field of Research

Epigenetics & Chromatin

Purity

99.17% (May vary between batches)

Solubility

DMSO:95 mg/mL (268.82 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (9.34 mM)

Smiles

Cc1cc2cc (NS (=O) (=O) c3ccc (cc3) C#N) ccc2n (C) c1=O

Molecular Formula

C18H15N3O3S

Molecular Weight

353.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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