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Nitroaspirin

Nitroaspirin (NCX 4016) is a nitric oxide-donating aspirin derivative that acts as an irreversible COX-1 inhibitor with antiplatelet effects. It demonstrates research utility in oncology, inducing apoptosis and cell cycle arrest in resistant ovarian cancer cells in vitro by suppressing EGFR/PI3K/STAT3 pathways and modulating Bcl-2 proteins.

Product Specifications

CAS Number

175033-36-0

Product Name Alternative

Inhibitor, NCX4016, NCX-4016, NCX 4016, Nitroaspirin, inhibit, COX, COX-1, Cyclooxygenase, Apoptosis

Field of Research

Cell Biology, Immunology & Inflammation, Neuroscience

Purity

98.45% (May vary between batches)

Solubility

DMSO:55 mg/mL (166.02 mM) ;10% DMSO+90% Corn Oil:5 mg/mL (15.09 mM)

Smiles

O (C (C) =O) C1=C (C (OC2=CC (CON (=O) =O) =CC=C2) =O) C=CC=C1

Molecular Formula

C16H13NO7

Molecular Weight

331.28

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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