KL1333
KL1333 is an orally bioavailable small molecule that acts as an NQO1 substrate to elevate cellular NAD+ levels. This NAD+ modulation activates the SIRT1/AMPK/PGC-1α axis, enhancing mitochondrial function and energy metabolism, as demonstrated in studies using MELAS patient fibroblasts.
Product Specifications
CAS Number
1800405-30-4
Product Name Alternative
Mitochondrial Metabolism, MitochondrialMetabolism, KL 1333, KL1333, KL-1333, inhibit, NQO1, NQO1 activator 1, Inhibitor
Field of Research
Metabolism Research
Purity
98.79% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (20.81 mM) ; DMSO:245 mg/mL (1019.73 mM)
Smiles
CC (C) c1nc-2c ([nH]1) C (=O) C (=O) c1ccccc-21
Molecular Formula
C14H12N2O2
Molecular Weight
240.26
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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