NS-2028
NS-2028 is a potent and selective soluble guanylyl cyclase (sGC) inhibitor, used to study nitric oxide signaling. It effectively blocks cGMP formation in vitro and inhibits NO-mediated smooth muscle relaxation. This compound is also applied in angiogenesis research, where it reduces VEGF-induced vascular permeability.
Product Specifications
CAS Number
204326-43-2
Product Name Alternative
Inhibit, NS 2028, NS2028, NS-2028, Inhibitor, Guanylatecyclase, Guanylate Cyclase, Guanylate cyclase, soluble Guanylyl Cyclase sGC, sGC
Field of Research
Pharmacology & Drug Discovery
Purity
99.44% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (18.58 mM) ; DMSO:250 mg/mL (929.2 mM)
Smiles
Brc1ccc2OCc3noc (=O) n3-c2c1
Molecular Formula
C9H5BrN2O3
Molecular Weight
269.05
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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