NS3623
NS3623 is a dual-action small molecule that both activates and inhibits the human ether-à-go-go-related gene (hERG) potassium channel. It modulates IKr and Ito currents, exhibiting antiarrhythmic properties useful for in vitro electrophysiology studies and cardiovascular research.
Product Specifications
CAS Number
343630-41-1
Product Name Alternative
Canine, Antiarrhythmic, cells, channels, cardiomyocytes, current, midmyocardial, ion, KcsA, inhibit, KV11.1, NS-3623, NS3623, NS 3623, Inhibitor, effect, Potassium, Potassium Channel, PotassiumChannel
Field of Research
Pharmacology & Drug Discovery
Purity
97.06% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.34 mM) ; DMSO:9.17 mg/mL (21.47 mM)
Smiles
FC (F) (F) c1cccc (NC (=O) Nc2ccc (Br) cc2-c2nnn[nH]2) c1
Molecular Formula
C15H10BrF3N6O
Molecular Weight
427.18
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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