NS5806
NS5806 is a small molecule activator of potassium currents that modulates KV4.3 and KV4.2 channels, particularly in complexes with KChIP2. It slows current decay and increases peak current amplitude (EC50 ~5.3 μM) . This tool compound is used in vitro to study cardiac transient outward potassium current (Ito) and neuronal A-type currents.
Product Specifications
CAS Number
426834-69-7
Product Name Alternative
Dacay, current, amplitudes, inhibit, KChIP2, Inhibitor, KcsA, KV4.2, KV4.3, NS 5806, NS5806, NS-5806, Ito, peak, Potassium Channel, PotassiumChannel
Field of Research
Pharmacology & Drug Discovery
Purity
97.95% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:3.3 mg/mL (5.75 mM) ; DMSO:250 mg/mL (435.49 mM)
Smiles
FC (F) (F) c1cc (NC (=O) Nc2c (Br) cc (Br) cc2-c2nn[nH]n2) cc (c1) C (F) (F) F
Molecular Formula
C16H8Br2F6N6O
Molecular Weight
574.07
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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