NSC-87877
NSC-87877 is a cell-permeable inhibitor of the SHP2 and SHP1 tyrosine phosphatases, with respective IC50 values of 0.318 μM and 0.355 μM, and it also suppresses DUSP26 activity. This compound is widely used in biochemical and cellular research to investigate phosphatase signaling roles in cancer, developmental biology, and immune regulation.
Product Specifications
CAS Number
56990-57-9
Product Name Alternative
DUSP26, Apoptosis, Inhibitor, HSP27, inhibit, neuroblastoma, NSC87877, NSC-87877, NSC 87877, p53, Phosphatase, shp1, shp2, SHP-1, SHP-2, p38, PPAR
Field of Research
Cell Biology, Metabolism Research, Neuroscience
Purity
97.35% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.18 mM) ; DMSO:4 mg/mL (8.71 mM)
Smiles
Oc1c (cc (c2cccnc12) S (O) (=O) =O) \N=N\c1ccc2cc (ccc2c1) S (O) (=O) =O
Molecular Formula
C19H13N3O7S2
Molecular Weight
459.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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