Opicapone
Opicapone (BIA 9-1067) is a third-generation catechol-O-methyltransferase (COMT) inhibitor used in Parkinson's disease research, notably for managing motor fluctuations. It reduces cellular ATP content with an IC50 of 98 μM, a mechanism studied in vitro. Its efficacy in prolonging levodopa's effect has been demonstrated in both preclinical and clinical research settings.
Product Specifications
CAS Number
923287-50-7
Product Name Alternative
COMT, BIA 9-1067, Inhibitor, inhibit, Opicapone
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
97.39% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.68 mM) ; DMSO:140 mg/mL (338.84 mM)
Smiles
Cc1c (Cl) c (C) [n+] ([O-]) c (Cl) c1-c1noc (n1) -c1cc (O) c (O) c (c1) [N+] ([O-]) =O
Molecular Formula
C15H10Cl2N4O6
Molecular Weight
413.17
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
