Oteseconazole
Oteseconazole (VT-1161) is an orally bioavailable antifungal agent that selectively and potently inhibits Candida albicans CYP51 (Kd <39 nM) without significantly affecting the human ortholog. It is a valuable research tool for studying fungal pathogenesis and has demonstrated efficacy in both in vitro assays and in vivo models of candidiasis.
Product Specifications
CAS Number
1340593-59-0
Product Name Alternative
VT1161, VT-1161, VT 1161, inhibit, Oteseconazole, Fungal, Inhibitor, Cytochrome P450, CYP51, CYPs, antifungal
Field of Research
Infectious Disease & Virology, Metabolism Research
Purity
99.07% (May vary between batches)
Solubility
DMSO:250 mg/mL (474.03 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (9.48 mM)
Smiles
O[C@@] (Cn1cnnn1) (c1ccc (F) cc1F) C (F) (F) c1ccc (cn1) -c1ccc (OCC (F) (F) F) cc1
Molecular Formula
C23H16F7N5O2
Molecular Weight
527.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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