P-1075
P-1075 is a potent and selective activator of SUR2-associated KATP channels (EC50 = 45 nM), including mitochondrial KATP. This activity underpins its use in research exploring cardioprotective mechanisms, with applications in both in vitro assays and in vivo models of ischemia-reperfusion injury.
Product Specifications
CAS Number
60559-98-0
Product Name Alternative
Inhibitor, inhibit, KcsA, P 1075, COS-7, adult rabbit cardiomyocytes, P1075, P-1075, Potassium Channel, PotassiumChannel, SUR2-KIR6
Field of Research
Pharmacology & Drug Discovery
Purity
99.35% (May vary between batches)
Solubility
DMSO:250 mg/mL (1080.85 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (21.62 mM)
Smiles
CCC (C) (C) N\C (NC#N) =N\c1cccnc1
Molecular Formula
C12H17N5
Molecular Weight
231.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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