P110δ-IN-1
P110δ-IN-1 (PWT-143) is a potent and selective small molecule inhibitor of the PI3K delta isoform, demonstrating an IC50 of 8.4 nM. This compound is a valuable research tool for studying B-cell signaling and immunology, with applications in both in vitro cellular assays and in vivo disease models for autoimmune disorders and hematological cancers.
Product Specifications
CAS Number
1595129-71-7
Product Name Alternative
Inhibit, Inhibitor, Phosphoinositide 3-kinase, PI3K, PWT143, PWT-143, PWT 143, p110δ, P110δ IN 1, P110δIN1, P-110δ-IN-1, P110δ-IN-1, P110delta-IN-1
Field of Research
Signal Transduction
Purity
99.75% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.65 mM) ; DMSO:5 mg/mL (8.27 mM)
Smiles
CN1CCC (CC1) c1ccccc1CC (C) (C) Nc1nc (nc (n1) -n1c (nc2ccccc12) S (C) (=O) =O) N1CCOCC1
Molecular Formula
C31H40N8O3S
Molecular Weight
604.77
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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