PCO371
PCO371 is a potent and selective small molecule agonist of the parathyroid hormone receptor 1 (PTH1R), demonstrating oral bioavailability. It serves as a research tool for studying bone metabolism and PTH signaling in both cellular assays and animal models.
Product Specifications
CAS Number
1613373-33-3
Product Name Alternative
THR, Thyroid hormone receptor, Thyroidhormonereceptor (THR), Thyroidhormonereceptor, thyroid hormone receptor-1 (PTHR1), Thyroid Hormone Receptor, Thyroid hormone receptor (THR), PTHR1, Inhibitor, inhibit, PCO 371, PCO371, PCO-371, 2,4-Imidazolidinedione, 1- (3,5-dimethyl-4- (2- ((4-oxo-2- (4- (trifluoromethoxy) phenyl) -1,3,8-triazaspiro (4.5) dec-1-en-8-yl) sulfonyl) ethyl) phenyl) -5,5-dimethyl-
Field of Research
Metabolism Research
Purity
97.17% (May vary between batches)
Solubility
DMSO:120 mg/mL (188.78 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (7.87 mM)
Smiles
Cc1cc (cc (C) c1CCS (=O) (=O) N1CCC2 (CC1) N=C (NC2=O) c1ccc (OC (F) (F) F) cc1) N1C (=O) NC (=O) C1 (C) C
Molecular Formula
C29H32F3N5O6S
Molecular Weight
635.65
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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