PF-4191834
PF-4191834 is a potent and selective 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 229 nM, showing no iron chelation or redox activity. It exhibits high selectivity over related lipoxygenases and cyclooxygenases. This inhibitor is a valuable research tool for studying leukotriene biology in inflammation and allergy models, both in vitro and in vivo.
Product Specifications
CAS Number
1029317-21-2
Product Name Alternative
LOX, inhibit, Lipoxygenase, Inhibitor, 5-LOX, PF-04191834, PF04191834, PF 4191834, PF4191834, PF-4191834, PF 04191834
Field of Research
Metabolism Research
Purity
98.46% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:2.5 mg/mL (6.35 mM) ; DMSO:50 mg/mL (127.06 mM)
Smiles
Cn1nccc1-c1ccc (Sc2cccc (c2) C2 (CCOCC2) C (N) =O) cc1
Molecular Formula
C22H23N3O2S
Molecular Weight
393.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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