PF 04531083
PF 04531083 is a selective NaV1.8 sodium channel blocker. This compound is a valuable research tool for investigating neuropathic and inflammatory pain mechanisms in both in vitro electrophysiology studies and in vivo animal models of pain.
Product Specifications
CAS Number
1079400-07-9
Product Name Alternative
Inhibit, NaV1.8, Nav1.8 channel, Na+ channels, Na channels, Inhibitor, SodiumChannel, Sodium Channel, PF04531083, PF-04531083, PF 04531083
Field of Research
Pharmacology & Drug Discovery
Purity
99.81% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.18 mM) ; DMSO:120 mg/mL (335.39 mM)
Smiles
COc1ccc (Cl) c (c1) -c1ccc (NC (=O) c2ccnn2C) nc1N
Molecular Formula
C17H16ClN5O2
Molecular Weight
357.79
Storage Conditions
-20°C
Notes
For research use only.
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