Pico145
Pico145 (HC-608) is a potent and selective small-molecule inhibitor of TRPC1/4/5 channels, exhibiting sub-nanomolar IC50 values against TRPC4 and TRPC5. It is a valuable research tool for studying the roles of these channels in pain, anxiety, and cancer in both cellular and animal models.
Product Specifications
CAS Number
1628287-16-0
Product Name Alternative
Inhibitor, HC 608, HC608, HC-608, inhibit, Pico 145, Pico145, Pico-145, Transient receptor potential channels, TRP Channel, TRPC4, TRPC4, cell assay, TRPC4-TRPC1, TRPC4-TRPC1, cell assay, TRPC5, TRPC5, cell assay, TRPC5-TRPC1, TRPC5-TRPC1, cell assay, TRPChannel, TRPV Channel, TRPVChannel
Field of Research
Pharmacology & Drug Discovery
Purity
98.71% (May vary between batches)
Solubility
DMSO:99 mg/mL (188.61 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.29 mM)
Smiles
Cn1c2nc (Oc3cccc (OC (F) (F) F) c3) n (Cc3ccc (Cl) cc3) c2c (=O) n (CCCO) c1=O
Molecular Formula
C23H20ClF3N4O5
Molecular Weight
524.88
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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