Ambrisentan
Ambrisentan (BSF 208075) is a selective endothelin receptor antagonist employed in pulmonary arterial hypertension (PAH) research. It is associated with a low incidence of serum enzyme elevations and has not been linked to clinically apparent liver injury. This small molecule is utilized in both in vitro binding assays and in vivo models of pulmonary hypertension.
Product Specifications
CAS Number
177036-94-1
Product Name Alternative
BSF 208075, BSF-208075, BSF208075, Ambrisentan, inhibit, LU 208075, LU208075, LU-208075, ET-A, Endothelin Receptor, EndothelinReceptor, Inhibitor
Field of Research
Pharmacology & Drug Discovery
Purity
99.65% (May vary between batches)
Solubility
Ethanol:6 mg/mL (15.86 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.29 mM) ; DMSO:45 mg/mL (118.92 mM)
Smiles
C ([C@H] (OC=1N=C (C) C=C (C) N1) C (O) =O) (OC) (C2=CC=CC=C2) C3=CC=CC=C3
Molecular Formula
C22H22N2O4
Molecular Weight
378.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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