GSK2256294A
GSK2256294A is a highly potent and selective soluble epoxide hydrolase (sEH) inhibitor, demonstrating sub-nanomolar IC50 values against human, rat, and mouse enzymes. This compound is a valuable research tool for investigating the role of sEH in cardiovascular, pulmonary, and metabolic diseases in both in vitro and in vivo models.
Product Specifications
CAS Number
1142090-23-0
Product Name Alternative
Inflammation, inhibit, oral, Inhibitor, Epoxide Hydrolase, EpoxideHydrolase, GSK 2256294, GSK2256294, GSK-2256294, GSK2256294A, GSK-2256294A, cardiovascular, COPD, cigarette smoke-exposure model, sEH
Field of Research
Metabolism Research
Purity
98.65% (May vary between batches)
Solubility
DMSO:4.48 mg/mL (10.01 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.23 mM)
Smiles
CNc1nc (C) nc (N[C@H]2CCC[C@H] (C2) C (=O) NCc2ccc (cc2C (F) (F) F) C#N) n1
Molecular Formula
C21H24F3N7O
Molecular Weight
447.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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