GW-870086

GW-870086 is a potent glucocorticoid receptor agonist with anti-inflammatory activity, demonstrating a pIC50 of 10.1 in NF-κB reporter assays using A549 cells. It is a valuable research tool for studying glucocorticoid receptor signaling and inflammation in both cellular and animal models.

Product Specifications

CAS Number

827319-43-7

Product Name Alternative

Inhibitor, GW870086, GW-870086, GW 870086, GlucocorticoidReceptor, Glucocorticoid Receptor, glucocorticoid receptor, glucocorticoid receptor, A549 NF-κB cells, inhibit

Field of Research

Metabolism Research

Purity

99.63% (May vary between batches)

Solubility

DMSO:11 mg/mL (19.66 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.57 mM)

Smiles

[H][C@@]12C[C@@H] (C) [C@] (OC (=O) C3C (C) (C) C3 (C) C) (C (=O) OCC#N) [C@@]1 (C) C[C@H] (O) [C@@]1 (F) [C@@]2 ([H]) C[C@H] (F) C2=CC (=O) C=C[C@]12C