GW7647
GW 7647 is a potent and selective PPARα agonist, demonstrating EC50 values of 6 nM, 1100 nM, and 6200 nM for human PPARα, PPARγ, and PPARδ, respectively. Its ability to reduce nitric oxide in macrophages underpins its utility in studying lipid metabolism and inflammation in both cellular and animal models.
Product Specifications
CAS Number
265129-71-3
Product Name Alternative
GW 7647, GW7647, GW-7647, Inhibitor, inhibit, PPARδ, PPARγ, PPARα, PPAR, Peroxisome proliferator-activated receptors
Field of Research
Metabolism Research, Molecular Biology
Purity
99.30% (May vary between batches)
Solubility
DMSO:81.67 mg/mL (162.45 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.98 mM)
Smiles
CC (C) (Sc1ccc (CCN (CCCCC2CCCCC2) C (=O) NC2CCCCC2) cc1) C (O) =O
Molecular Formula
C29H46N2O3S
Molecular Weight
502.75
Storage Conditions
-20°C
Notes
For research use only.
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