HLM006474
HLM006474 is a pan-E2F inhibitor that blocks the DNA-binding activity of E2F transcription factors, such as E2F4, with an IC50 of 29.8 μM in A375 melanoma cells. This small molecule is a useful research tool for studying cell cycle regulation, proliferation, and oncogenic signaling pathways in various in vitro cancer models.
Product Specifications
CAS Number
353519-63-8
Product Name Alternative
Early 2 Factor (E2F), Inhibitor, HLM 006474, HLM006474, HLM-006474, inhibit, E2F4 DNA-binding
Field of Research
Cell Biology
Purity
98.45% (May vary between batches)
Solubility
DMSO:15.625 mg/mL (39.11 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.5 mM)
Smiles
CCOc1ccc (cc1C) C (Nc1ccccn1) c1ccc2ccc (C) nc2c1O
Molecular Formula
C25H25N3O2
Molecular Weight
399.48
Storage Conditions
-20°C
Notes
For research use only.
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