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Tegaserod maleate

Tegaserod maleate (SDZ-HTF-919) is a selective 5-HT4 receptor agonist developed by Novartis. It was previously approved for IBS with constipation but was withdrawn due to cardiovascular risk concerns. This compound remains a valuable research tool for studying serotonergic pathways in gastrointestinal motility and related in vitro and in vivo models.

Product Specifications

CAS Number

189188-57-6

Product Name Alternative

5-HT, 5HTReceptor, 5-hydroxytryptamine Receptor, 5HT Receptor, 5-HT Receptor, bowel, inhibit, irritable, SDZ-HTF 919, SDZ-HTF919, SDZ-HTF-919, HTF 919, HTF919, HTF-919, IBS, Inhibitor, Gastrointestinal, Serotonin Receptor, Sert (Sodium-dependent), syndrome, Tegaserod, Tegaserod maleate, Tegaserod Maleate

Field of Research

Cell Biology, Neuroscience, Pharmacology & Drug Discovery

Purity

98.00% (May vary between batches)

Solubility

DMSO:125 mg/mL (299.43 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.79 mM)

Smiles

C (=C\C (O) =O) \C (O) =O.C (=NNC (NCCCCC) =N) C=1C=2C (NC1) =CC=C (OC) C2

Molecular Formula

C20H27N5O5

Molecular Weight

417.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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