IDH-305
IDH-305 is a brain-penetrant, orally bioavailable small molecule inhibitor with high selectivity for mutant IDH1 (R132H/C) over the wild-type enzyme. It is a research tool for investigating mutant IDH1-driven pathologies, such as glioma and cholangiocarcinoma, in both cellular and animal models.
Product Specifications
CAS Number
1628805-46-8
Product Name Alternative
Inhibit, Isocitrate Dehydrogenase (IDH), IDH1WT, IDH1R132C, IDH 305, IDH1-R132C, IDH1R132H, IDH1-R132H, IDH1-WT, IDH305, IDH-305, Inhibitor
Field of Research
Metabolism Research
Purity
99.13% (May vary between batches)
Solubility
DMSO:100 mg/mL (203.89 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.16 mM)
Smiles
C[C@H] (F) [C@H]1COC (=O) N1c1ccnc (N[C@@H] (C) c2cc (C) c (cn2) -c2ccnc (c2) C (F) (F) F) n1
Molecular Formula
C23H22F4N6O2
Molecular Weight
490.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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