Incyclinide
Incyclinide (CMT-3) is a non-antimicrobial tetracycline derivative that potently inhibits matrix metalloproteinases (MMPs) . It has demonstrated efficacy in suppressing invasiveness and growth of various cancers, including prostate, colon, and melanoma, in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
15866-90-7
Product Name Alternative
CMT 3, CMT3, CMT-3, COL 3, COL3, COL-3, Inhibitor, Matrix metalloproteinases, inhibit, MT1-MMP, Incyclinide, MMP
Field of Research
Protein Biochemistry
Purity
97.81% (May vary between batches)
Solubility
DMSO:95 mg/mL (255.83 mM)
Smiles
[H][C@@]12Cc3cccc (O) c3C (=O) C1=C (O) [C@]1 (O) C (=O) C (C (N) =O) =C (O) C[C@]1 ([H]) C2
Molecular Formula
C19H17NO7
Molecular Weight
371.34
Storage Conditions
-20°C
Notes
For research use only.
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