MKC8866
MKC8866 is a potent and selective IRE1 RNase inhibitor with an IC50 of 0.29 μM in human cell-based assays. It suppresses the production of pro-tumorigenic factors in breast cancer cells and has demonstrated in vivo efficacy by inhibiting tumor growth in prostate cancer models.
Product Specifications
CAS Number
1338934-59-0
Product Name Alternative
Inositol requiring enzyme 1, Inhibitor, MKC 8866, MKC8866, MKC-8866, IRE1 RNase, IRE1, inhibit
Field of Research
Cell Biology
Purity
96.57% (May vary between batches)
Solubility
DMSO:3.62 mg/mL (10.02 mM)
Smiles
COc1cc2c (C) c (CC (=O) N3CCOCC3) c (=O) oc2c (C=O) c1O
Molecular Formula
C18H19NO7
Molecular Weight
361.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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