Clobetasol propionate
Clobetasol propionate is a potent synthetic corticosteroid that activates glucocorticoid receptors to modulate gene expression, exerting anti-inflammatory effects by inhibiting phospholipase A2 and arachidonic acid release. It is widely used in research models of dermatological inflammation, including in vitro assays and in vivo studies of psoriasis and eczema.
Product Specifications
CAS Number
25122-46-7
Product Name Alternative
Cytochrome P450, CYPs, Dermovate, dermatoses, Clobetasol, Clobetasol 17-propionate, Clobetasol propionate, Clobetasol Propionate, corticosteroid, CGP9555, CGP-9555, CGP 9555, CCl 4725, Inhibitor, GlucocorticoidReceptor, Glucocorticoid Receptor, inhibit, psoriasis, Temovate
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
98.44% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:86 mg/mL (184.17 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.07 mM) ; Ethanol:16 mg/mL (34.26 mM)
Smiles
CCC (=O) OC1 (C (C) CC2C3CCC4=CC (=O) C=CC4 (C) C3 (F) C (O) CC12C) C (=O) CCl
Molecular Formula
C25H32ClFO5
Molecular Weight
466.97
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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