JNJ-38877618
JNJ-38877618 (OMO-1) is a potent and selective Met kinase inhibitor, demonstrating low nanomolar IC50 values against both wild-type and mutant forms. It is a valuable research tool for investigating Met-driven oncogenesis in cellular assays and has shown antitumor efficacy in preclinical in vivo models.
Product Specifications
CAS Number
943540-74-7
Product Name Alternative
CMet/HGFR, c-Met/HGFR, cMet, c-Met, Inhibitor, HGFR, inhibit, mutant Met, JNJ 38877618, JNJ38877618, JNJ-38877618, Met, OMO 1, OMO1, OMO-1, wt Met
Field of Research
Signal Transduction
Purity
98.84% (May vary between batches)
Solubility
DMSO:4.5 mg/mL (12.02 mM)
Smiles
FC (F) (c1nnc2ccc (nn12) -c1ccncc1) c1ccc2ncccc2c1
Molecular Formula
C20H12F2N6
Molecular Weight
374.35
Storage Conditions
-20°C
Notes
For research use only.