JNJ-64619178
JNJ-64619178 is a potent, orally bioavailable, and pseudo-irreversible PRMT5 inhibitor with an IC50 of 0.14 nM. It demonstrates promising anti-tumor efficacy in both in vitro and in vivo models of lung cancer, making it a valuable tool for oncology research.
Product Specifications
CAS Number
2086772-26-9
Product Name Alternative
HistoneMethyltransferase, Histone Methyltransferase, Inhibitor, JNJ64619178, JNJ-64619178, JNJ 64619178, inhibit, Onametostat, PRMT5
Field of Research
Epigenetics & Chromatin
Purity
98.44% (May vary between batches)
Solubility
DMSO:120 mg/mL (248.26 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (6.83 mM)
Smiles
Nc1nc2cc (CC[C@H]3C[C@H] ([C@H] (O) [C@@H]3O) n3ccc4c (N) ncnc34) ccc2cc1Br
Molecular Formula
C22H23BrN6O2
Molecular Weight
483.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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