K-756
K-756 is a potent and selective tankyrase (TNKS) inhibitor, exhibiting IC50 values of 31 nM and 36 nM against TNKS1 and TNKS2, respectively. This small molecule is a valuable research tool for studying Wnt/β-catenin signaling in cancer biology and has been utilized in both cellular and in vivo models to investigate pathway inhibition.
Product Specifications
CAS Number
130017-40-2
Product Name Alternative
Bcatenin, beta-catenin, betacatenin, K 756, K-756, K756, Inhibitor, inhibit, PARP, TNKS1, TNKS2, Wnt, Wnt/b-catenin, Wnt/betacatenin, Wnt/β-catenin, poly ADP ribose polymerase, βcatenin
Field of Research
Epigenetics & Chromatin, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.68% (May vary between batches)
Solubility
DMSO:4.5 mg/mL (10.38 mM)
Smiles
COc1cc2ncnc (N3CCC (CN4Cc5ccccc5NC4=O) CC3) c2cc1OC
Molecular Formula
C24H27N5O3
Molecular Weight
433.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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