KY1220
KY1220 is a small molecule Wnt/β-catenin pathway inhibitor that destabilizes β-catenin and Ras, exhibiting an IC50 of 2.1 μM in HEK293 reporter assays. It is a useful research tool for studying oncogenic signaling in cancers and for conducting both in vitro and in vivo experiments targeting Wnt-driven pathologies.
Product Specifications
CAS Number
292168-79-7
Product Name Alternative
Wnt, Wnt/b-catenin, Wnt/betacatenin, Wnt/β-catenin, βcatenin, β-catenin, KY 1220, KY1220, KY-1220, inhibit, Inhibitor, HEK293 reporter cells, bcatenin, Beta catenin, beta-catenin, betacatenin
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Purity
99.66% (May vary between batches)
Solubility
DMSO:100 mg/mL (318.15 mM)
Smiles
[O-][N+] (=O) c1ccc (cc1) -n1cccc1\C=C1/NC (=S) NC1=O
Molecular Formula
C14H10N4O3S
Molecular Weight
314.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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