LDN-212320
LDN-212320 (OSU-0212320) is a small molecule activator of the glutamate transporter EAAT2. It potently upregulates EAAT2 protein expression, increasing levels more than sixfold at concentrations below 5 μM within 24 hours. This compound is a valuable research tool for studying EAAT2 function in models of excitotoxicity, such as amyotrophic lateral sclerosis (ALS) and other neurological disorders, in both cellular and animal studies.
Product Specifications
CAS Number
894002-50-7
Product Name Alternative
EAAT2, OSU 0212320, OSU0212320, OSU-0212320, Excitatory amino acid transporter 2, Glutamate transporter 1, GLT-1, LDN 212320, LDN212320, LDN-212320, LDN 0212320, LDN0212320, LDN-0212320, LDN/OSU 0212320, LDN/OSU0212320, LDN/OSU-0212320
Field of Research
Metabolism Research
Purity
98.13% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.82 mM) ; DMSO:16.67 mg/mL (56.82 mM)
Smiles
Cc1ccccc1CSc1ccc (nn1) -c1ccccn1
Molecular Formula
C17H15N3S
Molecular Weight
293.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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