Lurbinectedin
Lurbinectedin (PM01183) is a synthetic small molecule that covalently binds to the minor groove of DNA, exhibiting potent antitumor activity. It is widely used in oncology research, demonstrating efficacy in both in vitro cytotoxicity assays and in vivo models of various cancers, including small cell lung cancer.
Product Specifications
CAS Number
497871-47-3
Product Name Alternative
RMG1, RMG2, Inhibitor, Lurbinectedin, PM-01183, PM 01183, PM01183, inhibit, DNA Alkylator/Crosslinker, DNA/RNA Synthesis
Field of Research
Cell Biology, Molecular Biology, Pharmacology & Drug Discovery
Purity
98.11% (May vary between batches)
Solubility
DMSO:15 mg/mL (19.11 mM)
Smiles
[H][C@@]12Cc3cc (C) c (OC) c (O) c3[C@@] ([H]) (N1C) [C@@]1 ([H]) N ([C@H]2O) [C@@]2 ([H]) COC (=O) [C@]3 (CS[C@]1 ([H]) c1c (OC (C) =O) c (C) c4OCOc4c21) NCCc1c3[nH]c2ccc (OC) cc12
Molecular Formula
C41H44N4O10S
Molecular Weight
784.87
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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