Lurbinectedin

Lurbinectedin (PM01183) is a synthetic small molecule that covalently binds to the minor groove of DNA, exhibiting potent antitumor activity. It is widely used in oncology research, demonstrating efficacy in both in vitro cytotoxicity assays and in vivo models of various cancers, including small cell lung cancer.

Product Specifications

CAS Number

497871-47-3

Product Name Alternative

RMG1, RMG2, Inhibitor, Lurbinectedin, PM-01183, PM 01183, PM01183, inhibit, DNA Alkylator/Crosslinker, DNA/RNA Synthesis

Field of Research

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Purity

98.11% (May vary between batches)

Solubility

DMSO:15 mg/mL (19.11 mM)

Smiles

[H][C@@]12Cc3cc (C) c (OC) c (O) c3[C@@] ([H]) (N1C) [C@@]1 ([H]) N ([C@H]2O) [C@@]2 ([H]) COC (=O) [C@]3 (CS[C@]1 ([H]) c1c (OC (C) =O) c (C) c4OCOc4c21) NCCc1c3[nH]c2ccc (OC) cc12