LX-1031
LX-1031 is a potent and selective small molecule inhibitor of tryptophan 5-hydroxylase (TPH), effectively reducing peripheral serotonin biosynthesis. This tool compound is utilized in preclinical research to investigate the role of peripheral 5-HT in conditions like irritable bowel syndrome (IBS) and inflammatory disorders, in both cellular and animal models.
Product Specifications
CAS Number
945976-76-1
Product Name Alternative
Inhibitor, LPAReceptor, LPA Receptor, inhibit, LX 1031, LX1031, LX-1031, Tryptophan hydroxylase, Tryptophan Hydroxylase
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
97.12% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.71 mM) ; DMSO:30 mg/mL (55.71 mM)
Smiles
COc1cccc (c1) -c1ccc (cc1) [C@@H] (Oc1cc (nc (N) n1) -c1ccc (C[C@H] (N) C (O) =O) cc1) C (F) (F) F
Molecular Formula
C28H25F3N4O4
Molecular Weight
538.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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