LY2940094
LY2940094 is a potent, selective, and orally bioavailable nociceptin receptor antagonist (Ki=0.105 nM) . It reduces ethanol self-administration in preclinical models, supporting its research use in studying addiction neurobiology and substance use disorders in both in vitro and in vivo systems.
Product Specifications
CAS Number
1307245-86-8
Product Name Alternative
Penetrate, self-administration, orally ethanol, BTRX 246040, BTRX246040, BTRX-246040, brain, disorder, depressive, major, OpioidReceptor, Opioid Receptor, LY 2940094, LY2940094, LY-2940094, Inhibitor, NOP receptor, inhibit
Field of Research
Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Purity
99.40% (May vary between batches)
Solubility
DMSO:41.67 mg/mL (86.64 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.16 mM)
Smiles
Cc1nn (cc1CN1CCC2 (CC1) OCC (F) (F) c1cc (Cl) sc21) -c1ncccc1CO
Molecular Formula
C22H23ClF2N4O2S
Molecular Weight
480.96
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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