LY2922470
LY2922470 is a potent and selective GPR40 agonist, demonstrating EC50 values of 7 nM (human), 1 nM (mouse), and 3 nM (rat) . It significantly lowers glucose while increasing insulin and GLP-1 secretion, making it a valuable research tool for studying metabolic diseases in both in vitro and in vivo models.
Product Specifications
CAS Number
1423018-12-5
Product Name Alternative
FFAR, Free Fatty Acid Receptor, human GPR40, GPR40, Inhibitor, mouse GPR40, inhibit, LY 2922470, LY2922470, LY-2922470, rat GPR40
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
93.34% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.41 mM) ; DMSO:125 mg/mL (262.83 mM)
Smiles
COc1cccc2CCCN (Cc3ccc (COc4ccc (cc4) [C@H] (CC (O) =O) C#CC) s3) c12
Molecular Formula
C28H29NO4S
Molecular Weight
475.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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