Doxifluridine
Doxifluridine is an oral prodrug of 5-fluorouracil (5-FU) designed for improved bioavailability. It is enzymatically converted to 5-FU, which inhibits DNA synthesis and RNA function, exerting antitumor activity. This compound is used in cancer research, including in vitro cytotoxicity assays and in vivo xenograft studies investigating fluoropyrimidine-based therapies.
Product Specifications
CAS Number
3094-09-5
Product Name Alternative
Analog, AMC 0101, AMC0101, AMC-0101, 5'-DFUR, 5-Fluoro-5'-deoxyuridine, DNA Synthesis, DNASynthesis, Doxifluridine, Inhibitor, NucleosideAntimetabolite, Nucleoside Antimetabolite/Analog, Nucleoside Antimetabolite, inhibit, Thymidine phosphorylase, Ro 21-9738, RNASynthesis, RNA Synthesis
Field of Research
Cell Biology, Molecular Biology, Pharmacology & Drug Discovery
Purity
99.47% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:45 mg/mL (182.79 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:2.5 mg/mL (10.15 mM) ; DMSO:55 mg/mL (223.4 mM)
Smiles
O[C@H]1[C@@H] (O[C@H] (C) [C@H]1O) N2C (=O) NC (=O) C (F) =C2
Molecular Formula
C9H11FN2O5
Molecular Weight
246.19
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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