Maytansinol
Maytansinol (Ansamitocin P-0) is a microtubule-destabilizing agent that disrupts microtubule polymerization in vitro. This mechanism supports its research use as a cytotoxic payload in antibody-drug conjugates (ADCs) and in studying mitosis and cell proliferation in cancer research models.
Product Specifications
CAS Number
57103-68-1
Product Name Alternative
Ansamitocin P 0, Ansamitocin P0, Ansamitocin P-0, Apoptosis, ADCCytotoxin, ADC Payload, ADC Cytotoxin, Microtubule Associated, MicrotubuleAssociated, Microtubule/Tubulin, inhibit, Inhibitor, Maytansinoids, Maytansinol
Field of Research
Cell Biology, Signal Transduction
Purity
98.80% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.54 mM) ; DMSO:35 mg/mL (61.94 mM)
Smiles
C[C@]12[C@@] (O1) ([C@H] (C) [C@@]3 (C[C@] (O) ([C@H] (OC) /C=C/C=C (\C) /CC4=CC (N (C) C (=O) C[C@@H]2O) =C (Cl) C (OC) =C4) NC (=O) O3) [H]) [H]
Molecular Formula
C28H37ClN2O8
Molecular Weight
565.05
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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