Tandutinib
Tandutinib (MLN518) is a potent and selective FLT3 inhibitor (IC50 = 0.22 μM) with additional activity against c-Kit and PDGFR. It demonstrates significant selectivity over CSF-1R, FGFR, EGFR, and KDR. This small molecule is a valuable research tool for studying FLT3-driven hematological cancers in both cellular and animal models.
Product Specifications
CAS Number
387867-13-2
Product Name Alternative
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
≥98% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.55 mM) ; Ethanol:6 mg/mL (10.66 mM) ; DMSO:50 mg/mL (88.86 mM)
Smiles
O (C) C1=CC=2C (=NC=NC2C=C1OCCCN3CCCCC3) N4CCN (C (NC5=CC=C (OC (C) C) C=C5) =O) CC4
Molecular Formula
C31H42N6O4
Molecular Weight
562.7
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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