Nesolicaftor
Nesolicaftor (PTI-428) is a CFTR amplifier that increases the production of the cystic fibrosis transmembrane conductance regulator protein. It is utilized in research to investigate CFTR biology and has been evaluated in both cellular assays and clinical studies for cystic fibrosis.
Product Specifications
CAS Number
1953130-87-4
Product Name Alternative
Autophagy, cystic fibrosis, Cystic fibrosis transmembrane conductance regulator, CFTR, Inhibitor, inhibit, Nesolicaftor, PTI 428, PTI428, PTI-428
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
98.64% (May vary between batches)
Solubility
DMSO:100 mg/mL (282.2 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.29 mM)
Smiles
C[C@@H] (O) c1nnc (o1) [C@H]1C[C@@H] (C1) NC (=O) c1cc (no1) -c1ccccc1
Molecular Formula
C18H18N4O4
Molecular Weight
354.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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Combination: 0.2mL tube, 36 wells; 0.5mL, 20 wells
